JunD/AP-1-mediated gene expression promotes lymphocyte growth dependent on interleukin-7 signal transduction.

Interleukin-7 (IL-7) is an essential cytokine for lymphocyte growth that has the potential for promoting immune reconstitution. This feature makes IL-7 an ideal candidate for therapeutic development. As with other cytokines, signaling through the IL-7 receptor induces the JAK/STAT pathway. However,...

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Autores principales:	Shannon M Ruppert, Mounir Chehtane, Ge Zhang, Haiyan Hu, Xiaoman Li, Annette R Khaled
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Public Library of Science (PLoS) 2012-01-01
Colección:	PLoS ONE
Acceso en línea:	http://europepmc.org/articles/PMC3285677?pdf=render
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