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Role of Phosphorylated Gonadotropin-Regulated Testicular RNA Helicase (GRTH/DDX25) in the Regulation of Germ Cell Specific mRNAs in Chromatoid Bodies During Spermatogenesis

GRTH/DDX25 is a member of the DEAD-box family of RNA helicases that play an essential role in spermatogenesis. GRTH knock-in (KI) mice with the human mutant GRTH gene (R242H) show loss of the phospho-species from cytoplasm with preservation of the non-phospho form in the cytoplasm and nucleus. GRTH...

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Hauptverfasser: Rajakumar Anbazhagan, Raghuveer Kavarthapu, Steven L. Coon, Maria L. Dufau
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020-12-01
Schriftenreihe:Frontiers in Cell and Developmental Biology
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fcell.2020.580019/full
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