Gene characteristics predicting missense, nonsense and frameshift mutations in tumor samples
Abstract Background Because driver mutations provide selective advantage to the mutant clone, they tend to occur at a higher frequency in tumor samples compared to selectively neutral (passenger) mutations. However, mutation frequency alone is insufficient to identify cancer genes because mutability...
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| Principais autores: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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BMC
2018-11-01
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| coleção: | BMC Bioinformatics |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s12859-018-2455-0 |
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