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Transgenerational Transcriptomic and DNA Methylome Profiling of Mouse Fetal Testicular Germline and Somatic Cells after Exposure of Pregnant Mothers to Tributyltin, a Potent Obesogen

Obesogens such as tributyltin (TBT) are xenobiotic compounds that promote obesity, in part by distorting the normal balance of lipid metabolism. The obesogenic effects of TBT can be observed in directly exposed (F1 and F2 generations) and also subsequent generations (F3 and beyond) that were never e...

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Autori principali: Keiko Shioda, Junko Odajima, Bruce Blumberg, Toshi Shioda
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2022-01-01
Serie:Metabolites
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Accesso online:https://www.mdpi.com/2218-1989/12/2/95
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