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A Chemical Screen Identifies Compounds Capable of Selecting for Haploidy in Mammalian Cells

Summary: The recent availability of somatic haploid cell lines has provided a unique tool for genetic studies in mammals. However, the percentage of haploid cells rapidly decreases in these cell lines, which we recently showed is due to their overgrowth by diploid cells present in the cultures. Base...

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Auteurs principaux: Teresa Olbrich, Maria Vega-Sendino, Matilde Murga, Guillermo de Carcer, Marcos Malumbres, Sagrario Ortega, Sergio Ruiz, Oscar Fernandez-Capetillo
Format: Artigo
Langue:Inglês
Publié: Elsevier 2019-07-01
Collection:Cell Reports
Accès en ligne:http://www.sciencedirect.com/science/article/pii/S2211124719308332
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