IL10-Deficiency in CD4+ T Cells Exacerbates the IFNγ and IL17 Response During Bacteria Induced Colitis

Background/Aims: IL10 is a key inhibitor of effector T cell activation and a mediator of intestinal homeostasis. In addition, IL10 has emerged as a key immunoregulator during infection with various pathogens, ameliorating the excessive T-cell responses that are responsible for much of the immunopath...

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Detalhes bibliográficos

Principais autores:	Virginia Seiffart, Julia Zoeller, Robert Klopfleisch, Munisch Wadwa, Wiebke Hansen, Jan Buer, Christian Riedel, Astrid M. Westendorf
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cell Physiol Biochem Press GmbH & Co KG 2015-07-01
Colecção:	Cellular Physiology and Biochemistry
Assuntos:	Citrobacter rodentium Interleukin 10 T helper cell 17 Colitis
Acesso em linha:	http://www.karger.com/Article/FullText/430295
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