Integration of tumor microenvironment and metabolic signatures reveals TMPI-defined prognostic and immunotherapy-relevant phenotypes in breast cancer

BackgroundBreast cancer heterogeneity presents a significant challenge for effective diagnosis and treatment. A deeper understanding of the tumor microenvironment (TME) and its metabolic dynamics is essential for addressing this complexity. This study explored the interplay between TME components an...

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Hlavní autoři:	Zhong Huang, Shuhui Lin, Ying Liang, Muhammad Khan, Weirui Chen, Xuefeng Li, Xiaolan Liu, Yunyu Wu, Jiacai Ye
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2026-06-01
Edice:	Frontiers in Pharmacology
Témata:	cancer metabolism cancer-associated fibroblasts immunotherapy transcriptomic analysis tumor microenvironment
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fphar.2026.1852654/full
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