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Dual role of interferon-gamma in the response of melanoma patients to immunotherapy with immune checkpoint inhibitors

Abstract Interferon-gamma (IFN-γ) is a cytokine produced mainly by immune cells and can affect cancer cells by modulating the activity of multiple signaling pathways, including the canonical Janus-activated kinase/signal transducer and activator of transcription (JAK/STAT) cascade. In melanoma, IFN-...

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Váldodahkkit: Piotr Wawrzyniak, Mariusz L. Hartman
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: BMC 2025-03-01
Ráidu:Molecular Cancer
Fáttát:
Liŋkkat:https://doi.org/10.1186/s12943-025-02294-x
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