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ASSOCIATION BETWEEN GENETIC VARIANTS IN TPMT AND NUDT15 AND THIOPURINE TOXICITY IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA

Introduction and objectives: Acute lymphoblastic leukemia (ALL) is characterized by accelerated proliferation of blasts in the bone marrow, reducing the production of normal blood cells and leading to accumulation of immature cells. Chemotherapeutic treatment of ALL is crucial for achieving remissio...

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Autors principals: A Nagel, G Suarez-Kurtz, M Mendes, M Emerenciano, BA Lopes
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2024-10-01
Col·lecció:Hematology, Transfusion and Cell Therapy
Accés en línia:http://www.sciencedirect.com/science/article/pii/S253113792401407X
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