Integrative imaging and transcriptomics implicate neutrophils in microvascular no-reflow after stroke

Abstract Background Ischemic stroke is a leading cause of adult disability and death, yet recanalization therapies that reopen occluded large arteries benefit only a subset of patients. Stroke patients can experience poor outcomes due to recanalization failure or the no-reflow phenomenon, where infl...

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Detalles Bibliográficos

Principais autores:	Sima Abbasi-Habashi, Mike Clarke, Yonglie Ma, Maria Guadalupe C. Real, Gabrielle M. Siegers, Glen C. Jickling, Ian R. Winship
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2026-04-01
Series:	Journal of Neuroinflammation
Assuntos:	Ischemic stroke No-reflow phenomenon Microvascular perfusion Collateral flow Capillary stalls Neutrophil depletion
Acceso en liña:	https://doi.org/10.1186/s12974-026-03785-4
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