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Human Neutrophils Respond to Complement Activation and Inhibition in Microfluidic Devices

Complement activation is key to anti-microbial defenses by directly acting on microbes and indirectly by triggering cellular immune responses. Complement activation may also contribute to the pathogenesis of numerous inflammatory and immunological diseases. Consequently, intense research focuses on...

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Principais autores: Sinan Muldur, Douangsone D. Vadysirisack, Sharan Ragunathan, Yalan Tang, Alonso Ricardo, Camil Elie Sayegh, Daniel Irimia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-11-01
coleção:Frontiers in Immunology
Assuntos:
complement
neutrophil
microfluidic “lab-on-a-chip
phagocytosis
infection
eculizumab
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2021.777932/full
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