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Erythropoietin (EPO) Increases Myelin Gene Expression in CG4 Oligodendrocyte Cells through the Classical EPO Receptor

Abstract Erythropoietin (EPO) has protective effects in neurodegenerative and neuroinflammatory diseases, including in animal models of multiple sclerosis, where EPO decreases disease severity. EPO also promotes neurogenesis and is protective in models of toxic demyelination. In this study, we asked...

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Principais autores: Ilaria Cervellini, Alexander Annenkov, Thomas Brenton, Yuti Chernajovsky, Pietro Ghezzi, Manuela Mengozzi
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2013-06-01
Serier:Molecular Medicine
Fag:
Myelin Gene
Medulla
Early Growth Response Gene
Myelin Oligodendrocyte Glycoprotein (MOG)
Myelin Basic Protein (MBP)
Online adgang:https://doi.org/10.2119/molmed.2013.00013
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