Reclassifying contralateral axillary metastasis: survival benefit of aggressive local therapy challenges stage IV designation

BackgroundContralateral axillary metastasis (CAM) is currently staged as M1 (stage IV) breast cancer, guiding treatment towards palliative systemic therapy. However, emerging evidence suggests CAM may behave as a locoregional event, potentially amenable to curative-intent strategies. This study aims...

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Principais autores:	Shanqing Liu, Yong Li, Yan Shen, Qixin Mao, Lianfang Li
格式:	Artigo
語言:	Inglês
出版:	Frontiers Media S.A. 2026-04-01
叢編:	Frontiers in Oncology
主題:	breast cancer Contralateral axillary metastasis Locoregional therapy overall survival staging
在線閱讀:	https://www.frontiersin.org/articles/10.3389/fonc.2026.1748851/full
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