A Compartmentalized Joint‐on‐chip (JoC) Model to Unravel the Contribution of Cartilage and Synovium to Osteoarthritis Pathogenesis

Abstract Osteoarthritis (OA) is a joint disorder causing pain and disability, yet effective treatments are limited due to incomplete understanding of pathogenic mechanisms involving complex tissue interactions. Articular cartilage degradation is a hallmark, resulting from an imbalance in extracellul...

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Bibliographic Details

Main Authors:	Cecilia Palma, Shima Salehi, Michela Anna Polidoro, Matteo Moretti, Marco Rasponi, Silvia Lopa, Paola Occhetta
Format:	Artigo
Language:	Inglês
Published:	Wiley 2025-11-01
Series:	Advanced Science
Subjects:	cartilage inflammation joint‐on‐chip mechanical stimulation organ‐on‐chip Osteoarthritis
Online Access:	https://doi.org/10.1002/advs.202500374
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