Analyzing the impact of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) on the reproductive system using network toxicology and molecular docking

Growing evidence suggests that perfluorinated compounds (PFCs) contribute to reproductive toxicity, with perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) being the most extensively studied. These chemicals are known to lower testosterone levels and compromise the integrity of the b...

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Hauptverfasser:	Liang Chen, Shanshan Liang, Jiaxin Li, Qian Li, Qingwen Sun
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2024-10-01
Schriftenreihe:	Heliyon
Schlagworte:	Perfluorooctanoic acid Perfluorooctane sulfonate Network pharmacology Molecular docking Reproductive toxicity
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2405844024154503
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