A randomized clinical trial of the impact of melatonin on influenza vaccine: Outcomes from the melatonin and vaccine response immunity and chronobiology study (MAVRICS)

Vaccine immunogenicity is affected by a variety of factors. Melatonin has been reported to affect immune responses to vaccines and infection. This was a randomized open-label trial – in which adults scheduled to receive the influenza vaccine were randomized to 5 mg melatonin or control to evaluate t...

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Principais autores:	Rachel U. Lee, Nora L. Watson, Gena L. Glickman, Lindsey White, Sandra D. Isidean, Chad K. Porter, Monique Hollis-Perry, Samuel R. Walther, Santina Maiolatesi, Martha Sedegah, Harini Ganeshan, Jun Huang, David A. Boulifard, Daniel Ewing, Appavu K. Sundaram, Elizabeth M. Harrison, Katherine DeTizio, Maria Belmonte, Arnel Belmonte, Sandra Inoue, Alexandra Easterling, Elizabeth S. Cooper, Janine Danko
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2024-12-01
coleção:	Human Vaccines & Immunotherapeutics
Assuntos:	Vaccine immunogenicity influenza vaccine melatonin vaccine adjuvant humoral immunity cellular immunity
Acesso em linha:	https://www.tandfonline.com/doi/10.1080/21645515.2024.2419742
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