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Targeting Senescence with Apigenin Improves Chemotherapeutic Efficacy and Ameliorates Age‐Related Conditions in Mice

Abstract Cellular senescence is a cell fate triggered by stressful stimuli and displays a hypersecretory feature, the senescence‐associated secretory phenotype (SASP). Senescent cell burden increases with aging and contributes to age‐related organ dysfunction and multiple chronic disorders. In this...

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Auteurs principaux: Hongwei Zhang, Qixia Xu, Zhirui Jiang, Rong Sun, Qun Wang, Sanhong Liu, Xin Luan, Judith Campisi, James L. Kirkland, Weidong Zhang, Yu Sun
Format: Artigo
Langue:Inglês
Publié: Wiley 2025-05-01
Collection:Advanced Science
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Accès en ligne:https://doi.org/10.1002/advs.202412950
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