Characterization of ¹⁸F-PM-PBB3 (¹⁸F-APN-1607) Uptake in the rTg4510 Mouse Model of Tauopathy

Misfolding, aggregation, and cerebral accumulation of tau deposits are hallmark features of Alzheimer’s disease. Positron emission tomography study of tau can facilitate the development of anti-tau treatment. Here, we investigated a novel tau tracer ¹⁸F-PM-PBB3 (¹⁸F-APN-1607) i...

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Hlavní autoři:	Chi-Chang Weng, Ing-Tsung Hsiao, Qing-Fang Yang, Cheng-Hsiang Yao, Chin-Yin Tai, Meng-Fang Wu, Tzu-Chen Yen, Ming-Kuei Jang, Kun-Ju Lin
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2020-04-01
Edice:	Molecules
Témata:	<sup>18</sup>F-FM-PBB3 <sup>18</sup>F-APN-1607 Alzheimer’s disease small animal PET tauopathy transgenic mice
On-line přístup:	https://www.mdpi.com/1420-3049/25/7/1750
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