Effects of Age and Estrogen on Skeletal Gene Expression in Humans as Assessed by RNA Sequencing.

Precise delineation of the specific genes and pathways altered with aging and estrogen (E) therapy may lead to new skeletal biomarkers and the development of novel bone therapeutics. Previous human bone studies, however, have been limited by only examining pre-specified genes and pathways. High-thro...

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Hlavní autoři:	Joshua N Farr, Matthew M Roforth, Koji Fujita, Kristy M Nicks, Julie M Cunningham, Elizabeth J Atkinson, Terry M Therneau, Louise K McCready, James M Peterson, Matthew T Drake, David G Monroe, Sundeep Khosla
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2015-01-01
Edice:	PLoS ONE
On-line přístup:	http://europepmc.org/articles/PMC4581624?pdf=render
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