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Accurate and sensitive interactome profiling using a quantitative protein-fragment complementation assay

Summary: An accurate description of protein-protein interaction (PPI) networks is key to understanding the molecular mechanisms underlying cellular systems. Here, we constructed genome-wide libraries of yeast strains to systematically probe protein-protein interactions using NanoLuc Binary Technolog...

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Principais autores: Natalia Lazarewicz, Gaëlle Le Dez, Romina Cerjani, Lunelys Runeshaw, Matthias Meurer, Michael Knop, Robert Wysocki, Gwenaël Rabut
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2024-10-01
Serija:Cell Reports: Methods
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Online dostop:http://www.sciencedirect.com/science/article/pii/S2667237524002637
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