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LXR Activation Induces a Proinflammatory Trained Innate Immunity-Phenotype in Human Monocytes

ObjectivesThe concept of trained innate immunity describes a long-term proinflammatory memory in innate immune cells. Trained innate immunity is regulated through reprogramming of cellular metabolic pathways including cholesterol and fatty acid synthesis. Here, we have analyzed the role of Liver X R...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Yahya Sohrabi, Glenn V. H. Sonntag, Laura C. Braun, Sina M. M. Lagache, Marie Liebmann, Luisa Klotz, Rinesh Godfrey, Florian Kahles, Johannes Waltenberger, Hannes M. Findeisen
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2020-03-01
Rangatū:Frontiers in Immunology
Ngā marau:
Urunga tuihono:https://www.frontiersin.org/article/10.3389/fimmu.2020.00353/full
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