HIV-1 Envelope Overcomes NLRP3-Mediated Inhibition of F-Actin Polymerization for Viral Entry

Summary: Purinergic receptors and nucleotide-binding domain leucine-rich repeat containing (NLR) proteins have been shown to control viral infection. Here, we show that the NLR family member NLRP3 and the purinergic receptor P2Y2 constitutively interact and regulate susceptibility to HIV-1 infection...

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Principais autores:	Audrey Paoletti, Awatef Allouch, Marina Caillet, Hela Saïdi, Frédéric Subra, Roberta Nardacci, Qiuji Wu, Zeinaf Muradova, Laurent Voisin, Syed Qasim Raza, Frédéric Law, Maxime Thoreau, Haithem Dakhli, Olivier Delelis, Béatrice Poirier-Beaudouin, Nathalie Dereuddre-Bosquet, Roger Le Grand, Olivier Lambotte, Asier Saez-Cirion, Gianfranco Pancino, David M. Ojcius, Eric Solary, Eric Deutsch, Mauro Piacentini, Marie-Lise Gougeon, Guido Kroemer, Jean-Luc Perfettini
格式:	Artigo
語言:	Inglês
出版:	Elsevier 2019-09-01
叢編:	Cell Reports
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2211124719302815
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