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Carrier Rate and Mutant Allele Frequency of GM1 Gangliosidosis in Miniature Shiba Inus (Mame Shiba): Population Screening of Breeding Dogs in Japan

GM1 gangliosidosis is a progressive, recessive, autosomal, neurodegenerative, lysosomal storage disorder that affects the brain and multiple systemic organs due to an acid β-galactosidase deficiency encoded by the <i>GLB1</i> gene. This disease occurs in the Shiba Inu breed, which is one of the most...

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Autors principals: Shahnaj Pervin, Md Shafiqul Islam, Yamato Yorisada, Aya Sakai, Shimma Masamune, Akira Yabuki, Tofazzal Md Rakib, Shinichiro Maki, Martia Rani Tacharina, Osamu Yamato
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2022-05-01
Col·lecció:Animals
Matèries:
carrier rate
mutant allele frequency
Mame Shiba Inu
GM1 gangliosidosis
canine <i>GLB1</i> gene
dog breeding
Accés en línia:https://www.mdpi.com/2076-2615/12/10/1242
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