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Ca<sup>2+</sup>/Sr<sup>2+</sup> Selectivity in Calcium-Sensing Receptor (CaSR): Implications for Strontium’s Anti-Osteoporosis Effect

The extracellular calcium-sensing receptor (CaSR) controls vital bone cell functions such as cell growth, differentiation and apoptosis. The binding of the native agonist (Ca<sup>2+</sup>) to CaSR activates the receptor, which undergoes structural changes that trigger a cascade of events along the c...

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Autors principals: Diana Cheshmedzhieva, Sonia Ilieva, Eugene A. Permyakov, Sergei E. Permyakov, Todor Dudev
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2021-10-01
Col·lecció:Biomolecules
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Accés en línia:https://www.mdpi.com/2218-273X/11/11/1576
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