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The impact of gut microbial signals on hematopoietic stem cells and the bone marrow microenvironment

Hematopoietic stem cells (HSCs) undergo self-renewal and differentiation in the bone marrow, which is tightly regulated by cues from the microenvironment. The gut microbiota, a dynamic community residing on the mucosal surface of vertebrates, plays a crucial role in maintaining host health. Recent e...

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Main Authors: Xiru Liu, Hao Zhang, Guolin Shi, Xinmin Zheng, Jing Chang, Quande Lin, Zhenhao Tian, Hui Yang
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
bone marrow microenvironment
gut microbiota
hematopoietic stem cells
hematologic malignancies
immune cells
broad-spectrum antibiotics
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1338178/full
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