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Adding pegylated interferon-α to nucleos(t)ide analogs improves HBsAg clearance in chronic hepatitis B with low-level viremia

IntroductionLow-level viremia (LLV) is associated with the progression of liver fibrosis and a high risk of hepatocellular carcinoma in patients with chronic hepatitis B (CHB). The present study aimed to compare the efficacy between nucleos(t)ide analogs (NAs) therapy and combination therapy of NAs...

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Principais autores: Lilin Wang, Junfeng Lu, Dan Liu, Shan Ren, Xinyue Chen, Zhongjie Hu, Sujun Zheng
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-08-01
Serier:Frontiers in Medicine
Fag:
low-level viremia
chronic hepatitis B
pegylated interferon-α
tenofovir alafenamide fumarate
HBsAg clearance
Online adgang:https://www.frontiersin.org/articles/10.3389/fmed.2025.1642961/full
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