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Seven DNA Methylation Biomarker Prediction Models for Monitoring the Malignant Progression From Advanced Adenoma to Colorectal Cancer

Advanced adenoma (AA) holds a significantly increased risk for progression to colorectal cancer (CRC), and we developed a noninvasive DNA methylation prediction model to monitor the risk of AA progression to CRC. We analyzed the differential methylation markers between 53 normal mucosa and 138 CRC t...

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Principais autores: Wei Wang, Xuecong Zhang, Xiaohui Zhu, Wenzhi Cui, Danli Ye, Guihui Tong, Dingpeng Huang, Juan Zhou, Xuwen Lai, Guangning Yan, Xia Li, Jianbing Fan, Hongwu Zhu, Chengyong Lei
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-05-01
Serier:Frontiers in Oncology
Fag:
cell-free DNA
advanced adenoma
colorectal cancer
monitoring
methylation model
Online adgang:https://www.frontiersin.org/articles/10.3389/fonc.2022.827811/full
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