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Bioinformatic elucidation of conserved epitopes to design a potential vaccine candidate against existing and emerging SARS-CoV-2 variants of concern

The COVID-19 pandemic caused by SARS-CoV-2 poses a significant adverse effects on health and economy globally. Due to mutations in genome, COVID-19 vaccine efficacy decreases. We used immuno-informatics to design a Multi epitope vaccine (MEV) candidate for SARS-CoV-2 variants of concern (VOCs). Henc...

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Gardado en:
Principais autores: Amber Rastogi, Sakshi Gautam, Manoj Kumar
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2024-08-01
Series:Heliyon
Assuntos:
SARS-CoV-2
COVID-19
Variants of concern
Immunogenic epitope
Multi-epitope
Vaccine design
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2405844024111607
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