Mouse Pharmacokinetics and In Vitro Metabolism of SH-11037 and SH-11008, Synthetic Homoisoflavonoids for Retinal Neovascularization

Cremastranone is a member of the homoisoflavanone family with anti-angiogenic activity in the eyes. SH-11037, a potent and selective synthetic homoisoflavonoid derived from cremastranone, was studied here for pharmacokinetics and metabolism characterization with a special focus on esterase-mediated...

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Principais autores:	Eun-yeong Kim, Bit Lee, Sangil Kwon, Timothy W. Corson, Seung-Yong Seo, Kiho Lee
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2022-10-01
coleção:	Pharmaceutics
Assuntos:	SH-11037 SH-11008 homoisoflavonoid pharmacokinetics drug metabolism hydrolysis
Acesso em linha:	https://www.mdpi.com/1999-4923/14/11/2270
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