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8-Chloroadenosine suppresses hepatocellular carcinoma progression via ADAR1/PPARγ axis-mediated lipid metabolism

The invasive and metastatic potential of hepatocellular carcinoma (HCC) is tightly linked to lipid metabolic reprogramming. However, existing knowledge of the molecular regulatory network governing lipid metabolism in HCC remains incomplete. This study reveals for the first time that ADAR1 promotes...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Jing Liu, Yongle Zhao, Xue Gong, Lin Yuan, Shengyong Yang, Wenwen Jian, Han Yan, Honglin Chen, Zhicheng Yang, Yiheng Sun, Tianle Gu, He Lu, Hongyun Zhao, Zeng Tu
Format: Artigo
Sprache:Inglês
Veröffentlicht: KeAi Communications Co., Ltd. 2026-09-01
Schriftenreihe:Genes and Diseases
Schlagworte:
8-Chloroadenosine
ADAR1
Hepatocellular carcinoma
Lipid metabolism
PPARγ
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2352304225003630
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