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Nonclassical MHC Ib-restricted CD8+ T Cells Recognize Mycobacterium tuberculosis-Derived Protein Antigens and Contribute to Protection Against Infection.

MHC Ib-restricted CD8+ T cells have been implicated in host defense against Mycobacterium tuberculosis (Mtb) infection. However, the relative contribution of various MHC Ib-restricted T cell populations to anti-mycobacterial immunity remains elusive. In this study, we used mice that lack MHC Ia (Kb-...

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Bibliografiske detaljer
Principais autores: Shaobin Shang, Sarah Siddiqui, Yao Bian, Jie Zhao, Chyung-Ru Wang
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2016-06-01
Serier:PLoS Pathogens
Online adgang:http://europepmc.org/articles/PMC4896622?pdf=render
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