Low nephron endowment increases susceptibility to renal stress and chronic kidney disease

Preterm birth results in low nephron endowment and increased risk of acute kidney injury (AKI) and chronic kidney disease (CKD). To understand the pathogenesis of AKI and CKD in preterm humans, we generated potentially novel mouse models with a 30%–70% reduction in nephron number by inhibiting or de...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Pamela I. Good, Ling Li, Holly A. Hurst, Ileana Serrano Herrera, Katherine Xu, Meenakshi Rao, David A. Bateman, Qais Al-Awqati, Vivette D. D’Agati, Frank Costantini, Fangming Lin
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical investigation 2023-02-01
Edice:	JCI Insight
Témata:	Nephrology
On-line přístup:	https://doi.org/10.1172/jci.insight.161316
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!