Action of trichostatin A on Alzheimer’s disease-like pathological changes in SH-SY5Y neuroblastoma cells

The histone deacetylase inhibitor, trichostatin A, is used to treat Alzheimer’s disease and can improve learning and memory but its underlying mechanism of action is unknown. To determine whether the therapeutic effect of trichostatin A on Alzheimer’s disease is associated with the nuclear factor er...

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Hlavní autoři:	Li-Hua Li, Wen-Na Peng, Yu Deng, Jing-Jing Li, Xiang-Rong Tian
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wolters Kluwer Medknow Publications 2020-01-01
Edice:	Neural Regeneration Research
Témata:	Alzheimer’s disease; amyloid-β peptide; autophagy; Keap1 signal; neurocytotoxicity; oxidative stress damage; SH-SY5Y cells; total antioxidant capacity; transcription factor Nrf2; TSA
On-line přístup:	http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=2;spage=293;epage=301;aulast=Li
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