Low‐dose immune tolerance induction in children with severe hemophilia A with high‐titer inhibitors: Type of factor 8 mutation and outcomes

Abstract Background No studies evaluated the role of F8 mutations in outcomes for low‐dose immune tolerance induction (ITI) in people with severe hemophilia A (SHA) with high‐titer inhibitors. Objectives To explore the association between F8 mutation types and low‐dose ITI outcomes in children with...

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Autori principali:	Jie Sun, Zekun Li, Gang Li, Kun Huang, Di Ai, Guoqing Liu, Wanru Yao, Xingjuan Xie, Hao Gu, Yingzi Zhen, Zhenping Chen, Runhui Wu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2022-10-01
Serie:	Research and Practice in Thrombosis and Haemostasis
Soggetti:	F8 mutation high‐titer inhibitor immune tolerance induction low‐dose predictor severe hemophilia A
Accesso online:	https://doi.org/10.1002/rth2.12824
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