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Aminopeptidases do not directly degrade tau protein

<p>Abstract</p> <p>Background</p> <p>Tau hyperphosphorylation and aggregation to form intracellular neurofibrillar tangles is prevalent in a number of tauopathies. Thus there is current interest in the mechanisms involved in Tau clearance. It was recently reported that Tau can be degraded by an amin...

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Autori principali: Hersh Louis B, Guan Hanjun, Chow K
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2010-11-01
Serie:Molecular Neurodegeneration
Accesso online:http://www.molecularneurodegeneration.com/content/5/1/48
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