Modulation of naïve mesenchymal stromal cells by extracellular vesicles derived from insulin-producing cells: an in vitro study

Abstract This study was to determine whether extracellular vesicles (EVs) derived from insulin-producing cells (IPCs) can modulate naïve mesenchymal stromal cells (MSCs) to become insulin-secreting. MSCs were isolated from human adipose tissue. The cells were then differentiated to generate IPCs by...

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Autors principals:	Mahmoud M. Gabr, Sawsan M. El-Halawani, Ayman F. Refaie, Sherry M. Khater, Amani M. Ismail, Mary S. Karras, Raghda W. Magar, Shorouk El Sayed, Malgorzata Kloc, Ahmed Uosef, Omaima M. Sabek, Mohamed A. Ghoneim
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2024-08-01
Col·lecció:	Scientific Reports
Matèries:	MSCs Differentiation Insulin-producing cells Extracellular vesicles Exosomes Diabetes
Accés en línia:	https://doi.org/10.1038/s41598-024-68104-4
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