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UHPLC-HRMS–based serum lipisdomics reveals novel biomarkers to assist in the discrimination between colorectal adenoma and cancer

The development of a colorectal adenoma (CA) into carcinoma (CRC) is a long and stealthy process. There remains a lack of reliable biomarkers to distinguish CA from CRC. To effectively explore underlying molecular mechanisms and identify novel lipid biomarkers promising for early diagnosis of CRC, a...

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Principais autores: Hongwei Chen, Jiahao Zhang, Hailin Zhou, Yifan Zhu, Yunxiao Liang, Pingchuan Zhu, Qisong Zhang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-07-01
Serier:Frontiers in Oncology
Fag:
colorectal adenoma
colorectal cancer
biomarkers
lipidomics
UHPLC-HRMS
Online adgang:https://www.frontiersin.org/articles/10.3389/fonc.2022.934145/full
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