Ponatinib as targeted therapy for FGFR1 fusions associated with the 8p11 myeloproliferative syndrome
The 8p11 myeloproliferative syndrome is a rare, aggressive myeloproliferative neoplasm characterized by constitutively active FGFR1 fusion proteins that arise from specific chromosomal translocations and which drive aberrant proliferation. Although FGFR1 inhibitors have shown in vitro activity again...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ferrata Storti Foundation
2013-01-01
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| coleção: | Haematologica |
| Acesso em linha: | https://haematologica.org/article/view/6521 |
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