Phosphatidylinositol 3-kinase-associated protein (PI3KAP)/XB130 crosslinks actin filaments through its actin binding and multimerization properties in vitro and enhances endocytosis in HEK293 cells.

Actin-crosslinking proteins control actin filament networks and bundles and contribute to various cellular functions including regulation of cell migration, cell morphology and endocytosis. Phosphatidylinositol 3-kinase-associated protein (PI3KAP)/XB130 has been reported to be localized to actin fil...

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Hlavní autoři:	Daisuke Yamanaka, Takeshi Akama, Kazuhiro Chida, Shiro Minami, Koichi Ito, Fumihiko Hakuno, Shin-Ichiro Takahashi
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2016-07-01
Edice:	Frontiers in Endocrinology
Témata:	Endocytosis Phosphatidylinositol 3-Kinase Actin actin-binding protein Crosslinking protein self-assembly
On-line přístup:	http://journal.frontiersin.org/Journal/10.3389/fendo.2016.00089/full
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