Comparative in silico/in vitro analysis of pharmacokinetic profiles of BET inhibitors

Pharmacokinetic limitations are a common cause of drug development failure, making early-stage profiling essential to mitigate financial risks and guide compound optimization. The computational tools capable of predicting pharmacokinetic properties offer a valuable resource for the prioritizing of c...

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Autors principals:	Koravović Mladen, Kovačević Milena, Jovanović Marija, Tasić Gordana, Mayasundari Anand, Nishiguchi Gisele, Marković Bojan, Ranković Zoran, Savić Vladimir
Format:	Artigo
Idioma:	Inglês
Publicat:	Serbian Chemical Society 2025-01-01
Col·lecció:	Journal of the Serbian Chemical Society
Matèries:	(+)-jq1 adme analysis admetlab 2.0 drug development
Accés en línia:	https://doiserbia.nb.rs/img/doi/0352-5139/2025/0352-51392500042K.pdf
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