Mitochondrial Dysfunction Correlates with Brain Amyloid Binding, Memory, and Executive Function in Down Syndrome: Implications for Alzheimer’s Disease in Down Syndrome

<b>Background/Objectives:</b> Mitochondrial dysfunction is increasingly recognized as a central contributor to neurodegenerative diseases and age-related cognitive decline. Individuals with Down syndrome (DS) are at high risk of neurodegeneration due to Alzheimer’s disease (AD). This study aims to e...

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Principais autores:	Jessica A. Beresford-Webb, Catherine J. McAllister, Alison Sleigh, Madeleine J. Walpert, Anthony J. Holland, Shahid H. Zaman
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2025-01-01
Series:	Brain Sciences
Assuntos:	Down syndrome Alzheimer’s disease dementia mitochondria
Acceso en liña:	https://www.mdpi.com/2076-3425/15/2/130
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