2-(Trihydroxyphenyl)thienopyrimidinones as Key Scaffolds for Targeting a Novel Allosteric Site of HIV-1 Integrase
A promising novel class of 2-(trihydroxyphenyl)thieno[2,3-<i>d</i>]pyrimidin-4(3<i>H</i>)-ones as HIV-1 integrase (IN) allosteric inhibitors is reported. All compounds were considerably more effective than the control compound LEDGIN-6, showing an inhibitory activity in the low micromolar range in b...
Gorde:
| Egile Nagusiak: | , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
MDPI AG
2025-12-01
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| Saila: | Molecules |
| Gaiak: | |
| Sarrera elektronikoa: | https://www.mdpi.com/1420-3049/30/24/4709 |
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