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Transformer-based InsightGWAS improves GERD genetic discovery via pretraining on GWAS for major depressive disorder

Abstract Gastroesophageal reflux disease (GERD) is a highly prevalent gastrointestinal disorder with complex genetic underpinnings.While genome-wide association studies (GWAS) have identified several GERD-associated loci, traditional GWAS approaches rely on stringent significance thresholds and may...

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Hlavní autoři: Yunhai Wei, Ziang Meng, Xianjin Wang, Yue Jiang, Huanxin Ding, Bichen Peng, Yingchao Song, Min Gao, Guangyong Zhang, Nan Zhang, Xiao Chang
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2026-01-01
Edice:Communications Biology
On-line přístup:https://doi.org/10.1038/s42003-025-09177-3
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