Structural MRI Reveals Cervical Spinal Cord Atrophy in the P301L Mouse Model of Tauopathy: Gender and Transgene-Dosing Effects

In primary tauopathies, the deposition of tau neurofibrillary tangles and threads as well as neurodegenerative changes have been found within the brain and spinal cord. While degenerative changes have been intensively studied in the brain using structural magnetic resonance imaging (MRI), MRI studie...

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Principais autores:	Thomas Sartoretti, Robert P. Ganley, Ruiqing Ni, Patrick Freund, Hanns Ulrich Zeilhofer, Jan Klohs
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-05-01
coleção:	Frontiers in Aging Neuroscience
Assuntos:	tau spinal cord magnetic resonance imaging frontotemporal dementia Alzheimer’s disease animal models
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fnagi.2022.825996/full
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