Intracellular PAF catabolism by PAF acetylhydrolase counteracts continual PAF synthesiss⃞
Stimulated inflammatory cells synthesize platelet-activating factor (PAF), but lysates of these cells show little enhancement in PAF synthase activity. We show that human neutrophils contain intracellular plasma PAF acetylhydrolase (PLA2G7), an enzyme normally secreted by monocytes. The esterase inh...
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| Hoofdauteurs: | , , , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Elsevier
2007-11-01
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| Reeks: | Journal of Lipid Research |
| Onderwerpen: | |
| Online toegang: | http://www.sciencedirect.com/science/article/pii/S0022227520424368 |
| Tags: |
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