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Angiotensin II triggers RIPK3-MLKL-mediated necroptosis by activating the Fas/FasL signaling pathway in renal tubular cells.

Our earlier studies proved that RIPK3-mediated necroptosis might be an important mode of renal tubular cell death in rats with chronic renal injury and the necroptotic cell death can be triggered by tumor necrosis factor-α (TNF-α) in vitro, but the triggering role of angiotensin II (AngII), which ex...

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Bibliografske podrobnosti
Principais autores: Yongjun Zhu, Hongwang Cui, Jie Lv, Guojun Li, Xiaoyan Li, Feng Ye, Liangbao Zhong
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2020-01-01
Serija:PLoS ONE
Online dostop:https://doi.org/10.1371/journal.pone.0228385
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