Flagellin shifts 3D bronchospheres towards mucus hyperproduction
Abstract Cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD) are associated with acute and chronic bacterial infections of the lung. Excessive differentiation of basal cells to mucus-producing goblet cells can result in mucus hyperproduction and loss of mucociliary clearance in the...
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| Principais autores: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2020-08-01
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| coleção: | Respiratory Research |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s12931-020-01486-x |
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