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Targeting MHC-I molecules for cancer: function, mechanism, and therapeutic prospects

Abstract The molecules of Major histocompatibility class I (MHC-I) load peptides and present them on the cell surface, which provided the immune system with the signal to detect and eliminate the infected or cancerous cells. In the context of cancer, owing to the crucial immune-regulatory roles play...

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Príomhchruthaitheoirí: Xiangyu Wu, Tianhang Li, Rui Jiang, Xin Yang, Hongqian Guo, Rong Yang
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: BMC 2023-12-01
Sraith:Molecular Cancer
Ábhair:
Rochtain ar líne:https://doi.org/10.1186/s12943-023-01899-4
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