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FGF21-FGFR1 controls mitochondrial homeostasis in cardiomyocytes by modulating the degradation of OPA1

Abstract Fibroblast growth factor 21 (FGF21) is a pleiotropic hormone secreted primarily by the liver and is considered a major regulator of energy homeostasis. Recent research has revealed that FGF21 could play an important role in cardiac pathological remodeling effects and prevention of cardiomyo...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Bing Yan, Zhu Mei, Yaohan Tang, Haixu Song, Hanlin Wu, Quanmin Jing, Xiaolin Zhang, Chenghui Yan, Yaling Han
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2023-05-01
Schriftenreihe:Cell Death and Disease
Online-Zugang:https://doi.org/10.1038/s41419-023-05842-9
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