Streptozotocin induces renal proximal tubular injury through p53 signaling activation
Abstract Streptozotocin (STZ), an anti-cancer drug that is primarily used to treat neuroendocrine tumors (NETs) in clinical settings, is incorporated into pancreatic β-cells or proximal tubular epithelial cells through the glucose transporter, GLUT2. However, its cytotoxic effects on kidney cells ha...
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| Główni autorzy: | , , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Portfolio
2023-05-01
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| Seria: | Scientific Reports |
| Dostęp online: | https://doi.org/10.1038/s41598-023-35850-w |
| Etykiety: |
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